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The JHU Proteomic Database is used to store raw, processed and final proteomic data from a large number of methods, technologies, clinical and physiological studies from cardiac studies through the National Heart, Lung and Blood Institute (NHLBI). This database will be used to mine information about proteins, protein patterns and post translational modifications (PTMs) and the associated methods and technologies. The data will be used to help create "protein profiles" to determine not only if disease is present, but the severity and progression of disease in the patient.

The database's schema was developed based on the Proteomics Experiment Data Repository (PEDRo) data model (Taylor et al (2003) Nature Biotech 21(3) pp.247-254). The current version is 0.21, which includes extensions to capture 2D gel experiment data and other modifications to provide lab and user based identification of entries. It is implemented on IBM's DB2 database platform.

JHU Proteomic Database Schema and Data Dictionary

 
   Related Web Links:
 

PEDRoWeb
(Taylor et al (2003) Nature Biotech 21(3) pp.247-254)

GelScape - A Web-based Gel Viewing & Annotation System
(Young et al (2004) Bioinformatics [Epub ahead of print])

Flicker Comparison of 2D Electrophoretic Gels
(Lemkin et al (1997) Electrophoresis 18(3-4) pp.461-70)

WebGel
(Lemkin et al (1999) Electrophoresis 20(18) pp.3492-507)

SWISS-PROT
(Appel et al (1996) Electrophoresis 17(3) pp.540-6)